Technological applications are essential to achieving malaria elimination objectives. Innovations in technology have aided and improved prevention, early diagnosis and treatment (EDAT), and surveillance aspects of malaria control and elimination programs. Some developments in mHealth improved data collection programmes to monitor malaria cases and increased monitoring of patient and treatment adherence. New progress in ICT systems advanced data harmonization, collection, and analytics strengthening malaria monitoring and surveillance programs. It helps real-time notification/reporting of malaria detected cases that leads to effective response intervention. New diagnostic technologies have improved accessibility, efficiency, and affordability in new case detection to enhance EDAT programmes. These approaches improved overall efficiency and accuracy in malaria case detection, provide medical results in real time, quicker identification of possible localized outbreaks, and improved access in hard to reach communities.

Technological advancements in RDT are paving the way for more precise and affordable diagnosis in remote areas with limited access to good quality microscopy services by the development of different mRDTs to fit different situations (from WHO). Malaria RDTs are now being produced with ultra-high sensitivity and the ability to detect low-level asymptomatic infections. Gene mutation technology, CRISPR/CAS-9, has made it possible to produce malaria resistant mosquitoes through the deletion of a single gene within the mosquito’s DNA. Molecular diagnostics allow for improved drug resistance and susceptibility testing at the point of care which is critical to combat antimicrobial resistance. Highly sensitive RDT (hsRDT) has been recommended by NMCPs and WHO as a diagnostic tool in malaria active case screening at the malaria elimination locations.